St. Marie is a town in Green Lake County, Wisconsin, United States.

As of the census[2] of 2000, there were 341 people, 135 households, and 98 families residing in the town.

There were 170 housing units at an average density of 5.1 per square mile (2.0/km2).

The racial makeup of the town was 99.12% White, 0.29% African American, and 0.59% from two or more races.

26.7% of all households were made up of individuals, and 11.9% had someone living alone who was 65 years of age or older.