St. Mary's Canossian College (Chinese: 嘉諾撒聖瑪利書院) is a Catholic girls secondary school in Tsim Sha Tsui, Kowloon, Hong Kong.

St. Mary's Canossian College was founded in 1900 by the Institute of the Canossian Daughters of Charity, a Catholic religious institute founded by Magdalene of Canossa of the ancient noble family of Verona, Italy, who was canonised on 2 October 1988 for her sanctity.

In the same year the Secondary Section was named "St. Mary's Canossian College", a grant-in-aid school for girls while the Primary Section was renamed "St. Mary's Canossian School".

The school has produced 2 perfect scorers "10As" in the history of Hong Kong Certificate of Education Examination (HKCEE) and 5 "Top Scorers" and "Super Top Scorers" in the history of Hong Kong Diploma of Secondary Education Examination (HKDSE).

[1][2] 7 x 5** "Top Scorers" are candidates who obtained perfect scores of 5** in each of the four core subjects and three electives.