St. Mary's Hospital was a Catholic hospital founded in 1866 by the Sisters of Charity of the Incarnate Word in Galveston, Texas, United States.

Founded in 1867,[1] it was the first private hospital in Texas.

[1] St. Mary's Hospital School of Nursing opened in 1907 and continued through 1968.

[1] The hospital was closed and sold in 1996 to the neighboring University of Texas Medical Branch.

This article relating to a hospital in Texas is a stub.