[10] It forms a part of the Lakeshore East development and overlooks the Chicago River near Lake Michigan.

[12] The structure consists of three interconnected towers, called "stems" with differing heights in a step-like arrangement.

[13] According to Studio Gang Architects, the tower "presents itself as three interconnected volumes of differing heights, moving rhythmically in and out of plane" as a result of the curvilinear design.

The design was described as "stacks of tapering, truncated pyramids that alternate between right-side-up and upside-down" by the Chicago Tribune.

[21] The tower has a notably smaller footprint than other supertalls in Chicago with a building height-to-core aspect ratio of 40-to-1.

[21] The tower uses coupled dual-core shear-wall assembly that connects the three buildings for wind resistance.

The two outer cores are tied together via a 508-ft-tall reinforced concrete spine, from floors 15 to 51 above the upper street grade.

[21] Six tanks, holding more than 400,000 US gallons (1,500,000 L; 330,000 imp gal) of water, counteract the movement of the wind.

[25] In March 2024, Chef Evan Funk's Tuscan-inspired "Tre Dita" opened in the St. Regis Chicago.

Edward Keegan of Crain's Chicago Business praised the design of the building, calling it "second only to Hancock in the gracefulness in its silhouette" and a "proud and soaring thing".