Saint Rose is a village in Clinton County, Illinois, United States.

Saint Rose is 5 miles (8.0 km) north-northwest of Breese.

According to the 2021 census gazetteer files, St. Rose has a total area of 0.59 square miles (1.53 km2), all land.

22.71% of all households were made up of individuals, and 13.53% had someone living alone who was 65 years of age or older.

This Clinton County, Illinois location article is a stub.