It was designed by Henry William Inwood as a chapel of ease for St Pancras Old Church (which resumed being a parish in its own right in 1852) and built between 1824 and 1827 by I. T.

[1] A Parliamentary grant paid for the construction, though local taxation funded the purchases of the chapel's interior decoration and the site itself.

It was consecrated on 11 March 1826 and soon afterwards it became famous for converting several local people from Roman Catholicism there.

The interior was the subject of two schemes, the 1874 one of J K Colling and the 1890 one of R C Reade—in the latter, traceried transoms were added to the windows and the west gallery taken out.

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