During the 1920s and early 1930s the missionary establishments in the southern Indian subcontinent laid foundations for a school in Hyderabad directly run under the church to provide education for the local people and impart religious teaching.

Once Pakistan acquired independence, it was clear that the nation would be an Islamic sovereign state, so a need arose for the gender-based separation of the coeducational school.

The Catholic Board of Education took charge of the development and running of the school and erected a church in the memory of Saint Francis Xavier for his services in central Asia and India.

[4] Running under the Christian administration, the schools imparted very high standards of education to upper and middle class students until 1972, when these were nationalised over by the socialist government of Zulfiqar Ali Bhutto.

The school provides for the needs of students from religious minorities and has separate classes for non-Muslims and Muslims in order to equip them with knowledge of their respective religions.

[6] The Christian administration was unsure how to go ahead with the new teaching curriculum but gathered teachers who could provide religious studies like Islamiyat.

While the students are initially given places in the sections, they are further divided into four different houses namely Unity, Faith, Discipline and Truth after the pillars of Quaid-e-Azam.

The school also has a marching band, which plays daily at the assembly and takes part in various competitions on a district and national level.