The church serves as a hub for evangelism, especially directed at young people who work in the surrounding financial district.

The church hosts monthly Opus Dei meetings,[2] and is also affiliated with the St Francis of Assisi Ramblers.

In 1850 the Catholic hierarchy was re-established in the United Kingdom, and the church was chosen as London's Pro-cathedral by Cardinal Wiseman.

"[5]The earliest known pipe organ associated with the parish dates from the second half of the eighteenth-century, and so may have been obtained for the post-Gordon-Riots chapel in White Street.

[6][7] It had previously been located in the Anglican church of 'St Nicholas, Gloucester; moved there in 1831 by the organ-building firm of Gray and Davison.

[8] The next pipe organ associated with the parish – for which there is detail – was installed around 1830 by the organ-building firm of Bevington,[9] and was a much more substantial instrument, better befitting the 1820s building.