A workplace ensemble comedy, Stacked revolves around Skyler Dayton (Pamela Anderson) who is tired of her non-stop partying lifestyle and bad choices in boyfriends.

Wanting a major life change, she wanders into Stacked Books, a small, family-run bookstore in the San Francisco area owned by Gavin Miller (Elon Gold) and his brother, Stuart (Brian Scolaro).

Stuart, however, is dazzled by Skyler's beauty and, much to Gavin's horror, offers her a job at their store, which she happily accepts as the first step in her quest for a steadier lifestyle.

Unhappy that she is going to be minding the till next to such an intimidating bombshell is the store's sole other employee, Katrina (Marissa Jaret Winokur), who doles out doses of realism and cynicism.

Rounding out the characters is the store's one steady customer, Harold March (Christopher Lloyd), a preeminent, but retired, rocket scientist.