Staffordsville is an unincorporated community in Giles County, Virginia, United States.

Staffordsville is located along Virginia State Route 100 and Walker Creek, 6 miles (9.7 km) south of Pearisburg.

Staffordsville has a post office with ZIP code 24167.

[2][3] The town is named after the Stafford Family, who were early settlers of the area.

This Giles County, Virginia state location article is a stub.