Playing for Northeast Louisiana (now Louisiana–Monroe), Humphries was quarterback on the team that won the 1987 NCAA Division I-AA Football Championship Game.
[2] He made his first professional start in 1990 in Phoenix against the Cardinals with regular starter Mark Rypien sidelined with an injury.
It started with the Chargers rallying from a 21–6 halftime deficit at home to defeat the Miami Dolphins (led by Hall of Fame quarterback Dan Marino) with a 22–21 victory in the AFC divisional playoffs, earning the Chargers a trip to the AFC Championship Game the next week at Pittsburgh.
Humphries executed the first successful two-point conversion in the Super Bowl (which was adopted by the NFL at the start of the 1994 season), throwing a pass to Mark Seay.
They were greeted by 70,000 fans at San Diego Jack Murphy Stadium upon arriving back from Pittsburgh.
[4] Humphries became a college football commentator, and also hosts his namesake celebrity golf tournament, which has raised more than $1 million over the years for Rady Children's Hospital in San Diego.
Humphries has served as the head girls basketball coach at Ouachita Christian School in Monroe, Louisiana since 2017.