Stanley Orville Spence (March 20, 1915 – January 9, 1983) was an American Major League Baseball center fielder who played from 1940 through 1949 for the Boston Red Sox (1940–41, 1948–49), Washington Senators (1942–47) and St. Louis Browns (1949).

A part-time player for the Boston Red Sox during two years, Spence played his first full-season for the Washington Senators in 1942 and he responded ending third in the American League batting race with a .323 average behind Ted Williams (.356) and Johnny Pesky (.331).

[1] After serving in the United States Army for World War II in 1945, he returned to the Senators a year later and hit a career-high 50 doubles with 10 triples and 16 home runs.

Spence hit a pivotal single in the 1947 Major League All-Star Game at Wrigley Field.

Prior to his at-bat, former teammate Bobby Doerr singled, stole second, and then took third on pitcher Johnny Sain's errant pickoff attempt.