In 1921 and 1922, the family renounced the Roman Catholic faith, and in 1924 they joined the newly emerging Orthodox Church under the leadership of the Bishop Gorazd Pavlík (who, like Nasadil, would later be martyred in the Second World War.)

[citation needed] Then he returned home and started working in the service of the church and also as a translator in Baťa's shoe factories in Zlín.

On 6 July 1931, he married Leopoldina b. Pestlová (Desanka) and the same year their son Dalibor called Stanko was born.

After his ordination, he began working as an auxiliary priest in the parish of Stara Moravica belonging to the Diocese of Upper Karlovac.

This Ustasha state liquidated religious minorities (Orthodox Serbs, Roma, and Jews).

On 23 May 1941 the Ustashas invaded the residence of the eparchial bishop Sava Trlajić in the village of Plaški.

Stanislav Nasadil died after being tortured on 28 June 1941, and his body was thrown into the Šaran pit, located about 1 km from the camp.