After the erection in early 1931 of a hangar and a clubhouse and offices with an observation/control tower on top, the aerodrome was officially opened on 2 June 1931 by the prime minister Ramsay MacDonald.

On 15 June 1932, T. Neville Stack departed from the aerodrome at the controls of Spartan Mailplane G-ABLI on the first leg of a flight to Karachi, India, carrying two passengers.

Pleasure flights were available to the public, but tragedy ensued when an Avro 504 biplane of Air Travel Ltd collided over the outskirts of Blackpool,[3] with Cobham's Westland Wessex monoplane.

The first scheduled air services from Stanley Park Aerodrome were operated by the short-lived United Airways to Hall Caine Airport, Isle of Man, during the summer of 1935 using eight-seat de Havilland Dragons.

[4] Railway Air Services (RAS) had operated schedules from Squires Gate from April 1935, but their flights moved to Stanley Park Aerodrome on 1 June 1937.

Vickers-Armstrongs (VA) established a major aircraft shadow factory at Squires Gate in 1940 for the production of large numbers of Vickers Wellington medium bombers.

Vickers took over most of the existing facilities at Stanley Park Aerodrome and used them, and five newly erected temporary Bellman hangars, to house a secondary assembly line.

A limited amount of charter flying was performed from Stanley Park Aerodrome during early 1946 by LAC using de Havilland Dragon Rapide biplane airliners.