The state highway follows Main Street through town and meets the eastern end of SR 186 (Beaton Avenue).

SR 35 intersects CSX's Portsmouth Subdivision and continues northeast as Meherrin Road.

SR 35 runs concurrently with US 58 Business northeast on a through truss bridge over the Nottoway River into the town of Courtland.

In the center of the county seat, US 58 Business turns south onto Main Street and SR 35 heads north and meets Norfolk Southern Railway's Franklin District at grade.

The state highway continues into Prince George County as Courtland Road to the village of Templeton.