The risk of damage starts to accrue after 30 minutes (time point 2) for convulsive status epilepticus.

[1] Other conditions that may also appear to be status epilepticus include low blood sugar, movement disorders, meningitis, and delirium, among others.

[1] After initial treatment with benzodiazepines, typical antiseizure drugs should be given, including valproic acid (valproate), fosphenytoin, levetiracetam, or a similar substance(s).

[1] The underlying cause, the person's age, and the length of the seizure are important factors in the outcome.

[1] Convulsive status epilepticus presents an urgent neurological condition, which is characterized by an elongated and uncontrollable onset of seizures in which a regular pattern of contraction and extension of the arms and legs will be observed from the patient.

[11] Nonconvulsive status epilepticus is a relatively long duration change in a person's level of consciousness without large-scale bending and extension of the limbs due to seizure activity.

[12] In the case of complex partial status epilepticus, the seizure is confined to a small area of the brain, normally the temporal lobe.

The cases of nonconvulsive status epilepticus are characterized by a long-lasting stupor, staring, and unresponsiveness.

Recent studies indicated 50% of cases involve patients that are semi-conscious in a way that they can respond but are confused spontaneously.

[7] In several countries outside North America, such as the Netherlands,[22] intravenous clonazepam is regarded as the drug of first choice.

[22] Cited advantages of clonazepam include a longer duration of action than diazepam and a lower propensity for the development of acute tolerance than lorazepam.

Phenytoin was once another first-line therapy,[25] although the prodrug fosphenytoin can be administered three times as fast and with far fewer injection site reactions.

[26] At present, these remain recommended second-line, follow-up treatments in the acute setting per guidelines by groups like Neurocritical Care Society (United States).

It was found that especially valproate in contrast to antiepileptic drugs is more effective to the treatment of nonconvulsive status epilepticus and more commonly used for it.

[31] Ketamine, an NMDA antagonist drug, can be used as a last resort for drug-resistant status epilepticus.

However, with optimal neurological care, adherence to the medication regimen, and a good prognosis (no other underlying uncontrolled brain or other organic disease), the person—even people who have been diagnosed with epilepsy—in otherwise good health can survive with minimal or no brain damage, and can decrease risk of death and even avoid future seizures.

[clarification needed] It was found that it takes a period of 1 to 14 days for the patient to reach the prodromal stage in which the episode is yet to come for the first time.

It can simply strike to hundreds of seizures per day, which is the stage that needed an urgent medical intervene in which the patient expected to be in the intensive care unit (ICU) as soon as possible.

[35] Prevalence It was found that status epilepticus is more prevalent among African Americans than Caucasian Americans by threefold in North London, and that Asian children have recorded a relatively higher susceptibility of developing the more severe form of febrile seizures.

[35] Aetiology Many studies have found out that age is the most related factor to the etiology of status epilepticus, since 52% of febrile seizures was found in children, while for adults acute cerebralvascular cases was more common, side by side with hypoxia and other metabolic causes.

[35] Allopregnanolone was being studied as a treatment for super-resistant status epilepticus,[36] but was found to have no benefit over placebo.