He served as acting commissioner of the U.S. Food and Drug Administration from April 1, 2015,[1] to February 21, 2016,[2] and from January to May 2017.

He completed residencies in internal medicine at the University of Colorado Health Sciences Center and in preventive medicine at Centers for Disease Control and Prevention (CDC).

He worked at the CDC, the US Public Health Service, and at the Bureau of Epidemiology of Pennsylvania.

In 2013, Ostroff joined the FDA as chief medical officer in the Center for Food Safety and Applied Nutrition and senior public health advisor to FDA's Office of Foods and Veterinary Medicine and was promoted to chief scientist in 2014.

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