Stephen Upson (1785 – August 24, 1824) was an American politician and lawyer.
Upson was born in Waterbury, Connecticut, and graduated from Yale College in 1804.
In 1807, Upson, moved to Hoover, Virginia, and later to Lexington, Georgia, in order to study law under William H. Crawford.
Upson died in 1824 and was buried in the Presbyterian Cemetery in Lexington.
On December 15, 1824, the Georgia General Assembly created Upson County and named it in his honor.