[7] In 1994 he starred as Joey Jackson, a poetic soul searching for the meaning of life, in Jim Morris' television film Blood on the Dole, part of the Alan Bleasdale Presents series for Channel 4.

[13] Walters would portray lead guest character Jack McCaffrey, a slippery cockney, in the two-part series one finale written by Paul Abbott.

[14] Between 1998 and 2000, Walters appeared in several episodic performances such as BBC's Pie in the Sky, opposite the late Richard Griffiths, Mikey Sullivan in Jimmy McGovern's crime drama Liverpool 1, Technician Fifth Grade John McGrath in HBO's WWII miniseries Band of Brothers (based upon historian Stephen E. Ambrose's 1992 book of the same name), and Scott in the BBC drama Nice Guy Eddie.

[15][16][17][18] In 2001, Walters starred as Knockoff in the BBC television production of writer Jim Cartwright's comedy Strumpet, opposite Christopher Eccleston.

[23][24] Walters would go on to portray the guest starring role of Dylan Forbes in the premiere episode of ITV's drama Murder City (2004), directed by Sam Miller, before a turn as Lord Gilbert Gifford in the BBC's 2005 dramatic mini-series The Virgin Queen.

[31][32] Walters would go on to play gangster Callum Rose, opposite fellow actor Stephen Graham, in BBC's 2012 production Good Cop.

[33][34][35] In the spring of 2013, Walters starred as real-life actor and activist Ricky Tomlinson in Ragged, a one-off drama for the Sky Arts Presents series, directed by comedian Johnny Vegas.

[42] Walters also reunited with previous co-star Sean Bean in "Tracie's Story", a critically acclaimed episode of 2013's The Accused, penned by Jimmy McGovern.

[48] From 2014 to 2016, opposite Sam Heughan, Caitriona Balfe and Graham McTavish, Walters portrayed the featured role of Angus Mhor in the television adaptation of Diana Gabaldon's best-selling Scottish time travel novel Outlander.

[54] In early 2017, Walters appeared in two episodes of AMC's post-apocalyptic original series Into the Badlands as The Engineer, an American warlord, opposite Daniel Wu and Nick Frost.

[55][56] He also appeared as DCI Mark Guinness in RTS Award-winning Little Boy Blue, a four-part factual drama that was based on the murder of Rhys Jones and written for ITV by Jeff Pope.

[66] Filmed in late summer 2018 and released in early 2022, Walters appeared as Steve Williams in ITV's four-part factual drama, Anne, alongside actress Maxine Peake.

[72] Walters' first feature film was director Jake Scott's 1999 anachronistic comedy Plunkett & Macleane, where he played the role of Dennis opposite Robert Carlyle.

[75] From there he featured in producer Matthew Vaughn's film Mean Machine (2001), a remake of the 1974 Burt Reynolds classic starring Vinnie Jones, as unpredictable bomb expert Nitro.

[76][77] He then played the role of Nazi skinhead Blowfish in Ronny Yu's film The 51st State (AKA-Formula 51) opposite Samuel L Jackson and Robert Carlyle.

[89] The WWII drama, directed by Adrian Vitoria, highlighted the story of Ian Fleming's 30 Commando Unit who were assigned to infiltrate behind enemy lines in the Nazi controlled snowy mountains of Norway.

[94] Second, in conjunction with James Roach and Tom Lox, is a short film entitled I'm Not Here, which explores Charles Manson and features Walters in the lead role.

[95] Walters recently completed short film Humpty Fu*king Dumpty, an in-depth look at Merseybeat musician Tommy Quickly, which he wrote and directed.