[3] Horvath's development of the DNA methylation based age estimation method known as epigenetic clock was featured in Nature magazine.

[5] In 2013 Horvath published a single author article on a multi-tissue age estimation method that applies to all nucleated cells, tissues, and organs.

[18] Horvath published the first article demonstrating that trisomy 21 (Down syndrome) is associated with strong epigenetic age acceleration effects in both blood and brain tissue.

[24] These cross sectional of epigenetic aging rates in blood confirm the conventional wisdom regarding the benefits of education, eating a high plant diet with lean meats, moderate alcohol consumption, physical activity and the risks associated with metabolic syndrome.

[25] Horvath and members of his lab developed a widely used systems biological data mining technique known as weighted correlation network analysis.