[4][7][8] His research focuses on developing and applying spatial statistics, mathematical, and computational methods within the discipline of quantitative geography.
[10] In 1994, he returned to the University of Newcastle as a professor of quantitative geography and the director of the North-East Regional Research Laboratory.
[10] Between 2011 and 2014, Fotheringham served as the director of the Centre for GeoInformatics and was a professor of quantitative geography at the University of St Andrews.
[11] Fotheringham contributed to GIScience and spatial statistics with his work in developing Geographically Weighted Regression (GWR).
[15] In GWR, regression coefficients (parameters) are estimated locally for each geographic location or point, allowing for the modeling of spatial heterogeneity.
[6] Geographically Weighted Regression is a cornerstone of GIS and spatial analysis, and is built into ArcGIS, as a package for the R (programming language), and as a plugin for QGIS.
Fotheringham addressed this problem in his 2015 paper titled "Geographical and Temporal Weighted Regression (GTWR).
[21][22][23] Fortheringham spoke at UCGIS on applying MGWR in a webinar titled Measuring the "Unmeasurable: Models of Geographical Context.