The creek is tidal for about one mile inland from the Hudson River.
The three mile stretch of Stockport Creek holds important spawning ground for the Hudson River's anadromous fish such as Blueback Herring, Alewives, Striped Bass, American Shad, White Perch, Smelt, Atlantic Sturgeon and Shortnose Sturgeon.
The tidal mudflats and littoral zones at the mouth of the river also host feeding grounds for Striped bass.
They also act as a nursery area for juvenile migratory fishes.
There is a large concentration of smallmouth bass in Stockport creek.