The game sets players in the year 2135 on a mission to save the Earth from colony-based, militant alien invaders using the MB-OG Raiga (Thunder Fang).

The craft's weapons include the Shotgun, Ion launcher, Vertical, Homing Missiles and Bomb attacks along with items such as Speed Ups, Shields and Extends.

The spacecraft can also obtain an Option weapon called the Auto Guard; three types of Auto Guards were available such as the target locking Beam Rifle, the powerful Solid Shooter and the standard Blaster item.

In 2005, Strato Fighter was released on the Xbox, as part of the Tecmo Classic Arcade collection.

In Japan, Game Machine listed Strato Fighter on their March 1, 1991 issue as being the third most-successful table arcade unit of the month.