Brown starred as Tammi Tyler, an ex-child actress who at 12 had stabbed her adult co-star to death after eating a cupcake laced with PCP.

Now, as an adult, Tammi worked as a waitress at the Funky Fox, a bar located in the Plaza del Toro.

Other businesses at the Plaza del Toro included a Chinese restaurant, Wok Don't Run, owned by Fanny Sue Chang (Amy Hill) and Althea (Loretta Fox), both of whom were lesbians; the Good Things gift shop, owned by Rafe (Maxwell Caulfield) and Bettina Bellingham (Eliza Coyle); and We Shoot You Video, which employed two college film graduates Barry (Chris Wylde) and Josh Macintosh (Jonathan Mangum), as well as a porn actress named Hedda Hummer (Allison Dunbar).

Bob Koherr, who had directed Brown in the 1997 movie Plump Fiction, played a biker named Blank and his identical brothers Blair and Blunt.

Strip Mall was one of two Comedy Central sitcoms cancelled in June 2001 due to cost reasons; the other was That's My Bush!