They are part of the larger group of QoIs (Quinone outside Inhibitors), which act to inhibit the respiratory chain at the level of Complex III.
The first parent natural products, strobilurins A and B, were extracted from the fungus Strobilurus tenacellus.
[4] Examples of commercialized strobilurin derivatives are azoxystrobin, kresoxim-methyl, picoxystrobin, fluoxastrobin, oryzastrobin, dimoxystrobin, pyraclostrobin and trifloxystrobin.
Strobilurins are mostly contact fungicides with a long half time as they are absorbed into the cuticle and not transported any further.
[5] Strobilurin A (also known as mucidin) is produced by Oudemansiella mucida, Strobilurus tenacellus, Bolinea lutea, and others.
[8] Its structure was originally incorrectly assigned and is now considered to be identical to that of strobilurin G, produced by B.
[7][8] A related material, hydroxystrobilurin D, with an additional hydroxyl group attached to the methyl of the main chain is produced by Mycena sanguinolenta.