It is centrally located along the Kuala Lumpur-Kuantan Highway on a 44-acre (18 ha) piece of land.

The hospital was to serve the growing healthcare needs of not only the district of Temerloh, but as a referral centre for Kuala Lipis, Raub, Maran, Bentong, Jerantut and Bera.

Construction of the hospital began in June 2002 and was completed on 15 January 2005, in a record period of 34 months.

Various healthcare services of the hospital were started in stages between March 2005 and 16 April 2005.

The hospital was officially opened by Sultan Haji Ahmad Shah of Pahang on 27 March 2006.