The Sunbury Line, formerly known as Sunbury Subdivision, is a rail line owned and operated by Norfolk Southern Railway which in turn is owned by the Norfolk Southern Corporation.

The Sunbury Line contains the Delaware, Lackawanna and Western's well-known Nicholson Cutoff railroad segment.

The PRR Wilkes-Barre Branch ran from the downtown Wilkes-Barre rail cluster southwest to Sunbury[1] along tracks on the east (left) shore of the North Branch Susquehanna River.

The line became part of the Pennsylvania Railroad and became known as the Wilkes-Barre Branch under PRR ownership.

The remainder of the PRR Wilkes-Barre Branch that is now part of the Sunbury Line runs from Sunbury to Hanover Township, to what was PRR's Buttonwood Yard, where it connected with the former Wilkes-Barre Connecting Railroad that extended from Hanover Township to Hudson, Pennsylvania.

In 1976, the Pennsylvania Railroad Wilkes-Barre Branch and the Delaware Lackawanna and Western Railroad main line were taken over by Conrail due to Penn Central and the Erie Lackawanna Railway being absorbed into Conrail, with trackage rights assigned to the Delaware and Hudson Railway.