Prior to debuting in films, Mabrey appeared in music videos, such as "Nookie" from Limp Bizkit.

Her breakthrough came after she played the lead role, man-eating alien Sara, in Species III (2004), supporting antagonist Charlie Mayweather in XXX: State of the Union (2005) and flight attendant 'Tiffany' in Snakes on a Plane (2006).

[2] Mabrey appeared in feature films XXX: State of the Union (2005), One Last Thing... (2005), Snakes on a Plane (2006) and Not Since You (2009).

On television, Mabrey guest-starred on CSI: Miami, House, Desperate Housewives, Mad Men and The Closer.

[9] Both Mabrey and Embry performed on the short-l lived television series Gotham Knights.