It was founded by dentist Albert Patrick and specialized in rhythm and blues.

Its artists included Jimmy Witherspoon, Paula Watson, Buddy Tate, Eddie Williams and his Brown Buddies (with Floyd Dixon), Big Jim Wynn, and Percy Mayfield.

[1][2] Supreme's two greatest hits were Paula Watson's "A Little Bird Told Me," which sold over a million copies,[3] and Jimmy Witherspoon's version of "Ain't Nobody's Business," recorded on Albert Patrick's request, which lasted 34 weeks on Billboard's Rhythm & Blues hit list.

The judge ruled in favor of Decca, stating that arrangements on an existing composition cannot be considered as property.

[3][5] In another lawsuit, the label lost its pressing and distribution partner Black & White Records after settling a dispute over Black & White selling its pressing line to Monogram in Canada.