"Guinea Pigs" (which was written by a practicing physician) depicted ways of fighting cancer, leading Merrill Panitt, critic for The Philadelphia Inquirer, to write, "the audience learned quite a bit about the disease" without sensationalism.
[10] The broadcast included an intermission during which Douglas Fairbanks Jr. and Mrs. Alben W. Barkley asked the audience to contribute to the American Cancer Society.
[10] Jack Gould's review in The New York Times of Sure as Fate's production of Macbeth called the modern-dress interpretation of that play "a commendable demonstration of television's willingness to experiment.
"[3] Media critic John Crosby praised Sure as Fate in a syndicated column that contained critiques of three suspense-themed dramatic programs that CBS broadcast on Tuesday nights.
"[11] Crosby wrote that each character in an episode, regardless of the size of the role, was portrayed in a way that made "a solid impact" and helped to move the plot along.