Susan J. Baserga is an American physician who is the William H. Fleming Professor of Molecular Biophysics and Biochemistry at Yale University.

She moved to Joan A. Steitz's laboratory at Yale University, where she started working on ribosome biogenesis.

[citation needed] Her research sought to identify how ribosome production is regulated in mammalian cells.

She uses Xenopus tropicalis as a model system for ribosomopathies, and is interested in Fanconi anemia repair factors.

[1] In 2020, Baserga was named the William H. Fleming Professor of Molecular Biophysics and Biochemistry.