Susan P. Holmes is an American statistician and professor at Stanford University.

She is noted for her work in applying nonparametric multivariate statistics, bootstrapping methods, and data visualization to biology.

She served as a tenured research scientist at INRA for ten years.

[3] She then taught at MIT and Harvard and was an associate professor of biometry at Cornell before moving to Stanford in 1998.

[1] She is married to fellow Stanford professor Persi Diaconis.