She was the third of six children born to the biologist Wilhelm von Nathusius and his wife, Marie and grew up in the family manor at Königsborn, where she received her education from tutors.
She continued her studies in Paris at the Académie Julian, where her teachers included Jean-Paul Laurens, Emile Auguste Carolus-Duran and Jean Jacques Henner.
[6] That same year, she began participating in the Paris Salon, where she won a silver medal for her portrayal of a Thuringian shoemaker smoking his pipe.
During the war, she remained in Halle, where she became involved in the "National Women's Work" program; establishing a sewing room that offered employment opportunities for military wives and widows.
[1] Among her best-known works are a series of portraits of Professors at the University of Halle and several military figures, including Gottlieb Graf von Haeseler and her younger brother, Wilhelm [de].