[4] The American writer John Gardner lived the last few years of his life in Susquehanna, where he died in a motorcycle accident in 1982.

[6] The New York and Erie Railroad (later reorganized as the Erie Railroad) built a rail line through the county in 1848, including the Starrucca Viaduct: a monumental stone structure spanning Starrucca Creek.

[8] The Susquehanna railroad station, which included a large hotel called the Starrucca House, opened in 1865.

By the end of the decade, Erie had moved all of its remaining shop operations to Meadville.

[9] Erie merged into the Erie–Lackawanna Railroad (EL) in 1960, and the latter ended passenger train service through Susquehanna on November 27, 1966.

[9] With the demise of the local railroad industry, Susquehanna now has many small resident-owned businesses scattered along Main Street.

Recent renovations to several Main Street buildings mark the first significant upturn in the local economy in several decades.

The Erie Railroad Station was added to the National Register of Historic Places in 1972.