She also played Brooke Alvarez on the comedic TV series, The Onion News Network, is an author and keynote speaker.

An Edsel Ford High School graduate, she has a Bachelor of Arts degree in communications from Michigan State University.

In 2010–2011, Sena portrayed Brooke Alvarez on the IFC series Onion News Network, a satire of television journalism.

In 2014, Sena appeared in several popular episodic television series, including Castle, How to Get Away with Murder, Sullivan & Son, and the Amazon pilot Down Dog.

She produced and co-starred in the comedic horror film Killer Party (2014), and starred in an independent movie.