While an undergraduate, she worked at Dynamic Cable in Coral Gables, Florida, where she was a sports director from 1984 to 1986, and was on the University of Miami water ski team.

In addition, she produced two magazine shows, Greyhound Racing America in Miami, Florida (1988–90) and Cowboys Special Edition in Irving, Texas (1990–91).

She was a weekend sports anchor and weekday feature reporter at WPEC-TV in West Palm Beach, Florida[6] from December 1991 until she moved to ESPN in 1993.

[8] As a member of the MNF team, Kolber helped the longtime franchise become the most-watched program in cable television history.

Kolber worked the ABC Sports broadcast of Super Bowl XL in Detroit in 2006 with Michele Tafoya and contributed to the network’s pre-game show.

[11] During the NFL off-season, Kolber served as an anchor on SportsCenter and as an on-site and studio host for ESPN's tennis coverage at the French Open from 2004 to 2006) and Wimbledon from 2003 to 2006 and in 2009.

She served as studio host for the network's coverage of the NHL on Fox, including both the 1999 Stanley Cup Finals and the Playoffs.

In March 1999, Kolber co-hosted a Fox non-sports presentation with Maury Povich, Opening the Lost Tombs: Live From Egypt, an archaeological event that promised to "unveil five-thousand year old mysteries."

After Tafoya left ESPN for NBC Sports at the end of the 2010 NFL season, ESPN used a rotating solo sideline reporter for the 2011 NFL season, with reporters Wendi Nix, Ed Werder, and Rachel Nichols stepping into the role each week, and Kolber used as a fill-in.

In the two weeks prior to Kolber's arrival in 2007, Brent Musburger was mysteriously absent from his position as lead host of NASCAR Countdown on the ABC/ESPN network.

On the week of the race on May 19, ESPN gave no reason for his absence but announced Kolber as the new host of Nextel Cup and Busch Series studio programming.

In 1995's ESPN Extreme Games for PlayStation, she has multiple video sequences hyping up the player, introducing levels, and hinting at secret areas.