It is the valley from the Brecon Beacons National Park to the sea at Swansea of the River Tawe in Wales.
Towns and villages include Clydach, Pontardawe, Ystradgynlais, Ystalyfera and Abercraf.
In its September 2005 document Towards a Valleys Strategy, Neath Port Talbot County Borough Council noted that a marked divide between the more remote communities at Ystalyfera and along the Twrch and Amman valleys and the reasonably prosperous southern communities of Pontardawe, Alltwen, Rhos, and Trebanos.
In 1878 opera singer Adelina Patti made her home at Craig-y-Nos Castle.
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