The women's 100 metre butterfly S13 event at the 2016 Paralympic Games took place on 8 September 2016, at the Olympic Aquatics Stadium.

Three heats were held.

The swimmers with the eight fastest times advanced to the final.

11:20 8 September 2016:[1] 11:24 8 September 2016:[1] 11:27 8 September 2016:[1] 19:39 8 September 2016:[2]