The women's 50 metre freestyle S10 event at the 2016 Paralympic Games took place on 9 September 2016, at the Olympic Aquatics Stadium.

Three heats were held.

The swimmers with the eight fastest times advanced to the final.

10:15 9 September 2016:[1] 10:18 9 September 2016:[1] 10:20 9 September 2016:[1] 18:35 9 September 2016:[2]