Sycamore is a home rule-class city in Jefferson County, Kentucky, United States.

It is bordered to the east by Douglass Hills, to the south and west by Blue Ridge Manor, and otherwise by consolidated Louisville/Jefferson County.

U.S. Route 60 (Shelbyville Road) forms the southern border of the community.

According to the United States Census Bureau, Sycamore has a total area of 0.02 square miles (0.04 km2), all land.

The racial makeup of the city was 83.02% White, 15.09% African American and 1.89% Asian.