The Blue Sox hosted the league's Opening Day for the inaugural season on 6 November 2010, when they played against the Canberra Cavalry,[3] and won the game 1–0.

As the sole team in New South Wales, they attracted interest beyond the Sydney metropolitan region; as far north as Newcastle, which hosted the former ABL franchise Hunter Eagles throughout the 1990s.

[7] Such was the demand to see professional baseball return to Sydney, several games had sold out well in advance of their scheduled dates,[6] including the season opener.

[17] The following month, Eddie Bray was appointed as general manager of the club, having held the same role with the Patriots in the 2010 Claxton Shield.

[18] Sydney's initial roster included two players—Chris Oxspring[19] and Koo Dae-Sung[20]—and manager Glenn Williams[21] with Major League experience.

With Oxspring also taking on the role of pitching coach, and a number of players with experience from international league's including Nippon Professional Baseball and Korea Baseball Organization, and the late addition to the roster of active Major Leaguers Trent Oeltjen[22] and Rich Thompson,[23] Sydney had the most experienced roster of any of the teams in the league.