She first stood on the ticket of Zambian Republican Party (ZRP) in 2001, then the Movement for Multi-Party Democracy (MMD) in 2003, then the Patriotic Front (PF) in 2011, and then the UPND in 2021.

By the time of the 2001 elections, she had joined the newly established Zambia Republican Party (ZRP), headed by former Minister of Defence Benjamin Mwila.

[5] In July 2015, the Anti-Corruption Commission arrested Ms. Masebo and charged her with two counts of abuse of authority of office when she served as minister of Tourism and Arts.

[6] Ahead of the 2016 general election, Sylvia Masebo decided to stand for Chongwe again, this time as the United Party for National Development candidate.

After losing her seat to Japhen Mwakalombe (who now stood for her previous party, the Patriotic Front), she decided to appeal the results, which was unsuccessful.