[6][7] Due to their presence at illness related sites, the Synergistota are suggested to be opportunistic pathogens but they can also be found in healthy individuals in the microbiome of the umbilicus and in normal vaginal flora.

[11] Seven other CSIs in important proteins including a 13 aa in RpoB were found to be uniquely present in Jonquetella, Pyramidobacter and Dethiosulfovibrio species indicating a close and specific relationship among these bacteria, which is also strongly supported by phylogenetic trees.

The identified molecular markers provide reliable means for the division of species from the phylum Synergistota into intermediate taxonomic ranks such as families and orders.

A. hydrogeniformans] Thermovirga lienii Aminiphilus circumscriptus Aminithiophilus ramosus Aminomonas paucivorans T. acidaminovorans T. velox Synergistes jonesii "Ca.

C. faecipullorum" Gilroy et al. 2021 C. evryensis C. porcorum Aminivibrio pyruvatiphilus Fretibacterium fastidiosum A. colombiense A. mobile Jonquetella anthropi P. piscolens P. porci D. salsuginis D. faecalis D. peptidovorans D. russensis The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LSPN)[18] and the National Center for Biotechnology Information (NCBI).