Syria I emerged out of Syria Coele, which during the reign of Antiochus III was one of the four satrapies in its region that included Phoenicia, Idumea, and an unknown territory that included Palestine.

[1] The Syria Coele region along the Euphrates was separated to form the province of Euphratensis.

[3] The region remained one of the most important provinces of the Byzantine Empire.

[4] Syria Prima was occupied by the Sasanians between 609 and 628, then recovered by the emperor Heraclius, but lost again to the advancing Muslims after the Battle of Yarmouk and the fall of Antioch.

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