It has jurisdiction over Syro-Malabar Catholics in the entirety of Great Britain: England, Scotland and Wales (the United Kingdom minus Northern Ireland).

Most of the faithful of this eparchy are British Indians with heritage in Kerala, where the Syro-Malabar Church is historically based.

The British eparchy, established in 2016, is the Syro-Malabar Catholic Church's fourth diocesan jurisdiction outside India, after the eparchies of Mississauga (Canada), Chicago (United States) and Melbourne (Australia).

The Syro-Malabar Catholic Church also has an Apostolic Visitor for Europe based in Rome, Bishop Mar Stephen Chirapanath, who oversees and ensures liaison between the pastoral missions and Mass centres in other parts of Europe, including Northern Ireland.

Its internal organization features a national coordination council and eight diocesan departments: Liturgy, Finance, Catechism, Faith Formation, Lay Association, Resolution Committee and Youth Association.