The eparchy includes ten civil districts of Karnataka, namely Bangalore, Bangalore Rural, Chikkaballapur, Kolar, Ramanagara, Tumkur, Mysore, Chamarajanagar, Mandya and Hassan.

[1] Infant Jesus Church, Henkel is the cathedral of the eparchy and the bishop's residence is at Kalenahalli, 6 km away from the city of Mandya.

The Eparchy of Mandya was created by bifurcating Syro-Malabar Catholic Diocese of Mananthavady.

The eparchy was created by Major Archbishop Varkey Vithayathil, by his decree on 18 January 2010.

St. Thomas Kakkanad.The canonical territory of Mandya diocese comprises four civil Districts of Mysore, Chamarajanagar, Mandya, Hassan and in August 2015 it is extended to Bangalore, Bangalore Rural, Chikkaballapur, Kolar, Ramanagara and Tumkur.