For more than 30 years, Sasitharan, has been actively involved as an actor, director and producer in the Singapore theatre scene.

He had 14 articles ranging from commentaries on Singapore culture and the arts to reviews of performances, exhibitions, talks and catalogue entries published both in Singapore and overseas.

[1] He then became the second Artistic Director of The Substation from April 1996 to August 2000 before he founded ITI with the late Kuo Pao Kun in 2000.

In 2015, Sasitharan starred in the segment "The Flame" of omnibus film 7 Letters.

Sasitharan is married to Kavita Kumari Ratty, an associate director at a university research institute.