Vaidynatha Iyer also had six sons namely, Mannarswamy, Ramu, Venkataraman and Subbaraman through another wife.

On completion of his studies, Seshagiri Iyer joined as an apprentice of the famous Madras lawyer of British origin, Eardley Norton.

[1] His name was considered for Diwan Bahadurship but was ultimately rejected by the Governor in favor of K. Narayana Row.

In 1916, disappointed at the very tough nature of the Intermediate Examination and the fact that very few Indian candidates had passed the examination, Seshagiri Iyer moved a resolution in the senate demanding that the pass mark for English be reduced to 30 percent.

Macphail uttered: "You bring rickshaw-wallahs and jhutkawallahs to the examination hall, and when they fail, you complain of slaughter".

[1] Seshagiri Iyer presided over the public meeting on 7 January 1926 at Soundarya Mahal in which the Madras Music Academy was formed.