Required for retaining emerin at the inner nuclear membrane.

However, the localization of TMEM43 in myocardial tissue is controversial discussed.

Franke et al. demonstrated that TMEM43 is localized at the intercalated disc but not at the nuclear envelope.

[7] In contrast Christensen et al. have shown that TMEM43 is mainly localized at the sarcolemma.

This article on a gene on human chromosome 3 is a stub.