986566873ENSG00000255690ENSMUSG00000043496Q7L0X0Q9DBY4NM_014817NM_025817NP_055632NP_080093KIAA0644, also known as TRIL or TLR4 interactor with leucine rich repeats, is a protein that in humans is encoded by the KIAA0644 gene.

It is, however, a member of the leucine-rich repeat family of proteins, which are known to be involved in protein-protein interactions.

TRIL is a component of the TLR4 complex and is induced in a number of cell types by lipopolysaccharide (LPS).

[6] The main isoform of the human protein is 811 amino long and is composed primarily of leucine (17%), alanine and arginine (~10%), and glycine (~ 8.5%) residues.

The KIAA0644 gene is neighbors to mRNA-cAMP responsive element binding gene downstream and mRNA carboxypeptidase and serine carboxypeptidase gene upstream [7][8] This article incorporates text from the United States National Library of Medicine, which is in the public domain.